Nowadays, the use of modern technologies to enhance the learning process and motivate students in the context of e-learning has gained attention. The aim of this study was to investigate the effect of distance learning based on Quick Response (QR) code technology on the learning and motivation of third-grade male elementary students in the city of Karaj in the subject of mathematics. This study was conducted experimentally using a pre-test and post-test design with two groups, control and experimental. The statistical population of the study included all third-grade male elementary students in the city of Karaj. From this population, 40 students were selected through purposive sampling and randomly divided into two groups of control and experimental (20 students in each group). The tools used included a learning test and Keller's motivation questionnaire. After administering the pre-test on learning and the motivation questionnaire to both groups, the control group was taught multiplication in mathematics through traditional classroom methods, while the content for the experimental group was made available through distance learning using the Shad platform based on QR code technology. Finally, the post-test on learning and the motivation questionnaire were administered to both groups. To analyze the data, univariate and multivariate covariance statistical tests were used. The results of the study showed a difference in the post-test scores of learning and motivation between the control and experimental groups. Therefore, the research hypotheses regarding the effectiveness of distance learning based on QR code technology on the learning and motivation of third-grade elementary students in mathematics were confirmed. According to the results of the study, the application of distance learning based on QR code technology is recommended to improve the learning and motivation of students in mathematics.