This research was conducted with the aim of systematically examining the application of artificial intelligence technology in assisting students with mathematical disabilities. The methodology of this study is qualitative and falls under the category of systematic review. The research field includes reputable scientific and research articles published between 2010 - 2025. The sample was selected purposefully based on specific criteria. The search strategy, based on the PRISMA method, was conducted in Iranian databases including Magiran, Irandoc, NoorMagz with keywords such as "artificial intelligence and dyscalculia," "artificial intelligence and cognitive disorders," and "artificial intelligence and learning disabilities." In foreign databases, the search was based on keywords like "Artificial intelligence and dyscalculia," "Artificial intelligence and dyslexia," and "Artificial intelligence and learning disability" using the Publish or Perish software across three databases: Web of Science, Scopus, and Google Scholar.The findings from the review of the studies indicate that artificial intelligence is applicable in diagnosis and screening, as well as personalizing education, creating an interactive environment, and enhancing the attention of children with learning disabilities. It is capable of improving children's performance in learning mathematics. Therefore, based on the findings of the conducted research, it can be concluded that artificial intelligence is an effective solution for educating students with mathematical disabilities and can reduce their learning difficulties in mathematics. However, it is suggested that further research in this area be expanded for a broader understanding and deeper insights.